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1. Nouveaux derives de la mescaline
   P. Macheras, G. Tsatsas
   Proceedings of the National Academy of Athens 55, 119-142 (1980)
   
2. Ring opening reactions 1. The triazinone ring opening of 2H-3,4-dihydro-as-triazino [3,4b] benzothiazol-3-one
   M. D. Kazanis, P. E. Macheras
   Chem. Chron. New Ser. 9, 201-205 (1980)
   [PDF]
3. Some considerations concerning the effect of an increased rate of oral absorption on drug levels of protein-bound drugs
   P Macheras, A Rosen
   Int. J. Pharm. 6, 175-178 (1980)
   [DOI: 10.1016/0378-5173(80)90090-3] [PDF]
4. Synthesis of 2-(5'-nitrofurylidene) azino-3-carboxy or carbethoxymethylbenzothiazolines and their activity against some gram-negative bacteria
   MD Kazanis, PE Macheras, NJ Legakis
   Eur. J. Med. Chem. 17, 291-292 (1982)
5. Comparative bioavailability studies of four commercial nitrofurantoin products
   P. E. Macheras
   Chem. Chron. New Ser. 12, 63-73 (1983)
   [PDF]
6. The bioequivalence factor
   P Macheras, A Rosen
   Pharm. Acta Helv. 58, 233-236 (1983)
7. Effect of absorption and elimination rates on the maintenance time of therapeutic drug levels - derivation of an equation for this time and its applications
   P Macheras, A Rosen
   Int. J. Pharm. 16, 353-359 (1983)
   [DOI: 10.1016/0378-5173(83)90155-2] [PDF]
8. The effect of protein on the dissolution of phenytoin
   A Rosen, P Macheras
   J. Pharm. Pharmacol. 36, 723-727 (1984)
   [DOI: 10.1111/j.2042-7158.1984.tb04859.x] [PDF]
9. Glc analysis following oxidation of phenytoin - an inexpensive method for routine determination of the drug in plasma
   P Macheras, A Rosen
   Pharmazie 39, 322-325 (1984)
   [DOI: 10.24355/dbbs.084-201811191154-0][PDF]
10. Is monitoring of drug in saliva reliable for bioavailability testing of a protein-bound drug - a theoretical approach
    P Macheras, A Rosen
    Pharm. Acta Helv. 59, 34-36 (1984)
11. Is monitoring of drug in saliva reliable for bioavailability testing of a protein-bound drug - a theoretical approach
    P Macheras, A Rosen
    Pharm. Acta Helv. 59, 34-36 (1984)
12. Quick method for the calculation of the absorption rate-constant of the linear one-compartment model using all available blood level data
    P Macheras
    Int. J. Pharm. 19, 339-343 (1984)
    [DOI: 10.1016/0378-5173(84)90063-2] [PDF]
13. Application of automated flow-injection analysis (fia) to dissolution studies
    M Koupparis, P Macheras, C Reppas
    Int. J. Pharm. 20, 325-333 (1984)
    [DOI: 10.1016/0378-5173(84)90179-0] [PDF]
14. Effect of protein on the absorption of phenytoin through everted gut preparations
    A Rosen, P Macheras
    J. Pharm. Pharmacol. 37, 154-158 (1985)
    [DOI: 10.1111/j.2042-7158.1985.tb05031.x] [PDF]
15. Milk drug coadministration
    P Macheras, C Reppas
    Pharmacology & Pharmacy 6, 152-153 (1985)
16. Automated flow-injection colorimetric determination of acetaminophen for assays and dissolution studies of multicomponent dosage forms
    M Koupparis, P Macheras, C Tsaprounis
    Int. J. Pharm. 27, 349-359 (1985)
    [DOI: 10.1016/0378-5173(85)90082-1] [PDF]
17. Graphical approach for determining whether absorption and elimination rate constants are equal in the one-compartment open model with 1st-order processes
    PE Macheras
    J. Pharm. Sci. 74, 582-584 (1985)
    [DOI: 10.1002/jps.2600740521] [PDF]
18. Developments in the concentration ratio method
    PE Macheras
    J. Pharm. Sci. 74, 1021-1021 (1985)
    [DOI: 10.1002/jps.2600740927] [PDF]
19. An automated flow injection-serial dynamic dialysis technique for drug protein-binding studies
    P Macheras, M Koupparis, C Tsaprounis
    Int. J. Pharm. 30, 123-132 (1986)
    [DOI: 10.1016/0378-5173(86)90072-4] [PDF]
20. The use of constant volume ultrafiltration for dissolution studies
    A Rosen, P Macheras, KD Howe
    Int. J. Pharm. 32, 171-175 (1986)
    [DOI: 10.1016/0378-5173(86)90176-6] [PDF]
21. Drug dissolution studies in milk using the automated flow-injection serial dynamic dialysis technique
    P Macheras, M Koupparis, C Tsaprounis
    Int. J. Pharm. 33, 125-136 (1986)
    [DOI: 10.1016/0378-5173(86)90046-3] [PDF]
22. Determination of nitrofurantoin in urine by derivative spectroscopy
    M Poulou, P Macheras
    Int. J. Pharm. 34, 29-34 (1986)
    [DOI: 10.1016/0378-5173(86)90006-2] [PDF]
23. Studies on drug milk freeze-dried formulations I. Bioavailability of sulfamethizole and dicumarol formulations
    PE Macheras, CI Reppas
    J. Pharm. Sci. 75, 692-696 (1986)
    [DOI: 10.1002/jps.2600750716] [PDF]
24. An automated flow-injection serial dynamic dialysis technique for drug-protein binding-studies
    PE Macheras, MA Koupparis
    Anal. Chim. Acta 185, 65-73 (1986)
    [DOI: 10.1016/0003-2670(86)80033-2] [PDF]
25. Studies on freeze-dried drug-milk formulations II. Effect of regenerated fluid volume on nitrofurantoin bioavailability
    PE Macheras, CI Reppas
    J. Pharm. Sci. 75, 1145-1150 (1986)
    [DOI: 10.1002/jps.2600751206] [PDF]
26. Method of residuals: Estimation of absorption and elimination rate constants having comparable values
    P. Macheras
    Biopharm. Drug Dispos. 8, 47-56 (1987)
    [DOI: 10.1002/bdd.2510080106] [PDF]
27. Dissolution of 4 controlled-release theophylline formulations in milk
    P Macheras, M Koupparis, E Apostolelli
    Int. J. Pharm. 36, 73-79 (1987)
    [DOI: 10.1016/0378-5173(87)90239-0] [PDF]
28. Dissolution and invitro permeation behaviors of dicumarol nitrofurantoin and sulfamethizole in the presence of protein
    P Macheras, C Reppas
    Int. J. Pharm. 37, 103-112 (1987)
    [DOI: 10.1016/0378-5173(87)90014-7] [PDF]
29. Analysis of linear one compartment open models
    P Macheras, A Rosen
    Am. J. Pharm. Educ. 51, 291-293 (1987)
30. Improvement without computer-assistance of the graphically estimated parameters of the linear one-compartment open model
    PE Macheras
    Biopharm. Drug Dispos. 8, 387-394 (1987)
    [DOI: 10.1002/bdd.2510080409] [PDF]
31. Effect of temperature and fat-content on the binding of hydrochlorothiazide and chlorothiazide to milk
    PE Macheras, MA Koupparis, SG Antimisiaris
    J. Pharm. Sci. 77, 334-336 (1988)
    [DOI: 10.1002/jps.2600770411] [PDF]
32. 2nd derivative UV spectrophotometric determination of hydrochlorothiazide and hydrochlorothiazide amiloride combination in tablets
    M Parissi-Poulou, V Reizopoulou, M Koupparis, P Macheras
    Int. J. Pharm. 51, 169-174 (1989)
    [DOI: 10.1016/0378-5173(89)90251-2] [PDF]
33. An invitro model for exploring CR theophylline milk-fat interactions
    P Macheras, M Koupparis, S Antimisiaris
    Int. J. Pharm. 54, 123-130 (1989)
    [DOI: 10.1016/0378-5173(89)90331-1] [PDF]
34. A new approach for the invivo evaluation of sustained-release dosage forms
    P Macheras, M Symillides, M Georgiacodis
    Int. J. Pharm. 52, 249-253 (1989)
    [DOI: 10.1016/0378-5173(89)90227-5] [PDF]
35. Toward a quantitative approach for the prediction of the fraction of dose absorbed using the absorption potential concept
    PE Macheras, MY Symillides
    Biopharm. Drug Dispos. 10, 43-53 (1989)
    [DOI: 10.1002/bdd.2510100106] [PDF]
36. Pharmacokinetics of acetaminophen after intramuscular administration
    P Macheras, M Parissi-Poulos, L Poulos
    Biopharm. Drug Dispos. 10, 101-105 (1989)
    [DOI: 10.1002/bdd.2510100111] [PDF]
37. Construction of a naproxen ion-selective electrode and its application to pharmaceutical analysis
    GN Valsami, PE Macheras, MA Koupparis
    Analyst 114, 387-391 (1989)
    [DOI: 10.1039/an9891400387] [PDF]
38. Effect of temperature and fat-content on the solubility of hydrochlorothiazide and chlorothiazide in milk
    PE Macheras, MA Koupparis, SG Antimisiaris
    J. Pharm. Sci. 78, 933-936 (1989)
    [DOI: 10.1002/jps.2600781111] [PDF]
39. 3-(3-Alkylamino-2-hydroxypropoxy)-derivatives of estratriene. Synthesis and preliminary pharmacological study
    M. Kazanis, P. Macheras, A. Vavayannis
    Chem. Chron. New Ser. 18, 41-46 (1989)
    [PDF]
40. Estimate of volume flow ratio of gastrointestinal (gi) fluids in humans using pharmacokinetic data
    P Macheras, C Reppas, JB Dressman
    Pharm. Res. 7, 518-522 (1990)
    [DOI: 10.1023/A:1015825018361] [PDF]
    Erratum
    P Macheras
    Pharm. Res. 8, 1078-1078 (1991)
    [DOI: 10.1023/A:1015833830347] [PDF]
41. Modified hplc analysis of diltiazem in plasma for pharmacokinetic studies
    M Parissi-Poulou, G Ismailos, P Macheras
    Int. J. Pharm. 62, R13-R16 (1990)
    [DOI: 10.1016/0378-5173(90)90244-X] [PDF]
42. Drug-binding and solubility in milk
    PE Macheras, MA Koupparis, SG Antimisiaris
    Pharm. Res. 7, 537-541 (1990)
    [DOI: 10.1023/A:1015881103340] [PDF]
43. Binding-studies of ions with cyclodextrins using ion-selective electrodes
    GN Valsami, PE Macheras, MA Koupparis
    J. Pharm. Sci. 79, 1087-1094 (1990)
    [DOI: 10.1002/jps.2600791210] [PDF]
44. Development of a computer program for the individualization of theophylline dosage regimens
    P. Macheras, C. Reppas, C. Tsaprounis
    Pneumon 2, 121-126 (1990)
    
45. Binding of drugs in milk - the role of casein in milk protein-binding - comments on the paper by Stebler and Guentert
    P Macheras, C Reppas, S Antimisiaris
    Pharm. Res. 8, 550-550 (1991)
    [DOI: 10.1023/A:1015832118593] [PDF]
46. Evaluation of controlled release formulations - estimation of the duration of the zero-order absorption and ascertainment of absorption kinetics
    P Macheras
    Biopharm. Drug Dispos. 12, 173-187 (1991)
    [DOI: 10.1002/bdd.2510120302] [PDF]
47. Unusual solubility behavior of cyclosporine-a in aqueous-media
    G Ismailos, C Reppas, JB Dressman, P Macheras
    J. Pharm. Pharmacol. 43, 287-289 (1991)
    [DOI: 10.1111/j.2042-7158.1991.tb06688.x] [PDF]
48. Bioavailability study of a freeze-dried sodium phenytoin-milk formulation
    P Macheras, G Ismailos, C Reppas
    Biopharm. Drug Dispos. 12, 687-695 (1991)
    [DOI: 10.1002/bdd.2510120906] [PDF]
49. Binding study of the fluorescence probe 1-anilino-8-naphthalenesulfonate to human plasma and human and bovine serum-albumin using potentiometric titration
    GN Valsami, PE Macheras, MA Koupparis
    Pharm. Res. 8, 888-892 (1991)
    [DOI: 10.1023/A:1015855613083] [PDF]
50. Fraction of the bioavailable dose remaining in the body at the time of peak plasma-concentration in a linear, open, one-compartment model
    P Macheras, C Reppas, M Symillides
    J. Pharm. Sci. 81, 110-112 (1992)
    [DOI: 10.1002/jps.2600810124] [PDF]
51. Equations for the fraction of bioavailable dose remaining in the body in the one-compartment model
    P Macheras, M Symillides, C Reppas
    Biopharm. Drug Dispos. 13, 229-232 (1992)
    [DOI: 10.1002/bdd.2510130309] [PDF]
52. On the assessment of the relative magnitude of rate constants in the linear open one-compartment model
    P Macheras, M Symillides, C Reppas
    J. Pharm. Sci. 81, 1231-1233 (1992)
    [DOI: 10.1002/jps.2600811223] [PDF]
53. Complexation studies of cyclodextrins with tricyclic antidepressants using ion-selective electrodes
    GN Valsami, MA Koupparis, PE Macheras
    Pharm. Res. 9, 94-100 (1992)
    [DOI: 10.1023/A:1018940013006] [PDF]
54. Determination of association constants in cyclodextrin drug complexation using the Scatchard plot - Application to beta-cyclodextrin-anilinonaphthalene sulfonates
    EE Sideris, GN Valsami, MA Koupparis, PE Macheras
    Pharm. Res. 9, 1568-1574 (1992)
    [DOI: 10.1023/A:1015808307322] [PDF]
55. Use of 1-anilino-8-napthalenesulphonate as an ion probe for the potentiometric study of the binding of sulfonamides to bovine serum-albumin and plasma
    A Angelakou, G Valsami, M Koupparis, P Macheras
    J. Pharm. Pharmacol. 45, 434-438 (1993)
    [DOI: 10.1111/j.2042-7158.1993.tb05571.x] [PDF]
56. Estimation of absorption rate-constant in a one-compartment model with the profile of the bioavailable dose eliminated as a function of multiples of half-life
    P Macheras, M Symillides, C Reppas
    J. Pharm. Sci. 82, 1298-1300 (1993)
    [DOI: 10.1002/jps.2600821226] [PDF]
57. Enhancement of cyclosporine-a solubility by d-alphatocopheryl-polyethylene-glycol-1000 succinate (tpgs)
    G Ismailos, C Reppas, P Macheras
    Eur. J. Pharm. Sci. 1, 269-271 (1994)
    [DOI: 10.1016/0928-0987(94)90021-3] [PDF]
58. The Cutoff Time Point of the Partial Area Method for Assessment of Rate of Absorption in Bioequivalence Studies
    P. Macheras, Mira Symillides & Christos Reppas
    Pharm. Res. 11, 831-834 (1994)
    [DOI: 10.1023/A:1018921622981] [PDF]
59. Effect of cyclodextrins on protein-binding of drugs - The diflunisal hydroxypropyl-beta-cyclodextrin model case
    EE Sideris, MA Koupparis, PE Macheras
    Pharm. Res. 11, 90-95 (1994)
    [DOI: 10.1023/A:1018901912619] [PDF]
60. Automated flow-injection serial dynamic dialysis technique in the study of drug-binding with cyclodextrins
    EE Sideris, CA Georgiou, MA Koupparis, PE Macheras
    Anal. Chim. Acta 289, 87-95 (1994)
    [DOI: 10.1016/0003-2670(94)80011-1] [PDF]
61. Automated flow-injection technique for use in dissolution studies of sustained-release formulations - Application to iron(II) formulations
    CA Georgiou, GN Valsami, PE Macheras, MA Koupparis
    J. Pharm. Biomed. Anal. 12, 635-641 (1994)
    [DOI: 10.1016/0731-7085(93)E0015-F] [PDF]
62. General treatment of competitive-binding as applied to the potentiometric ion probe technique - Application to the interaction of nonsteroidal antiinflammatory drugs with bovine serum-albumin
    AT Angelakou, EE Sideris, GN Valsami, MA Koupparis, PE Macheras
    J. Pharm. Sci. 83, 1150-1154 (1994)
    [DOI: 10.1002/jps.2600830816] [PDF]
63. Evaluation of different metrics as indirect measures of rate of drug absorption from extended-release dosage forms at steady-state
    C Reppas, LF Lacey, ON Keene, P Macheras, A Bye
    Pharm. Res. 12, 103-107 (1995)
    [DOI: 10.1023/A:1016246922519] [PDF]
64. Carrier-mediated transport can obey fractal kinetics
    P Macheras
    Pharm. Res. 12, 541-548 (1995)
    [DOI: 10.1023/A:1016201929304] [PDF]
65. Determination of fractal reaction dimension in dissolution studies
    G Valsami, P Macheras
    Eur. J. Pharm. Sci. 3, 163-169 (1995)
    [DOI: 10.1016/0928-0987(95)00005-X] [PDF]
66. Construction of a diflunisal ion sensor and its use in automated flow-injection methods for assay, content uniformity, and dissolution studies of formulations
    P Solich, PE Macheras, MA Koupparis
    J. Pharm. Sci. 84, 889-894 (1995)
    [DOI: 10.1002/jps.2600840720] [PDF]
67. The Geometric Mean Functional Relationship Approach to Linear Regression in Pharmaceutical Studies: Application to the Estimation of Binding Parameters
    Georgia Valsami and Panos Macheras
    Pharm. Sci. 1, 551-554 (1995)
    [DOI: 10.1111/j.2042-7158.1995.tb00377.x] [PDF]
68. A Fractal Approach to Heterogeneous Drug Distribution: Calcium Pharmacokinetics
    P. Macheras
    Pharm. Res. 13, 663-670 (1996)
    [DOI: 10.1023/A:1016031129053] [PDF]
69. Fractal geometry, fractal kinetics and chaos en route to biopharmaceutical sciences
    P. Macheras, Argyrakis, P. & Polymilis
    Eur. J. Drug Metabolism Pharmacokinetics 21, 77-86 (1996)
    [DOI: 10.1007/BF03190255] [PDF]
70. An improved intercept method for the assessment of absorption rate in bioequivalence studies
    P. Macheras, Mira Symillides & Christos Reppas
    Pharm. Res. 13, 1755-1758 (1996)
    [DOI: 10.1023/A:1016421630290] [PDF]
71. Development of a potentiometric kinetic method for drug adsorption studies: The chlorpromazine-charcoal model case
    J Atta-Politou, M Koupparis, P Macheras
    Eur. J. Pharm. Sci. 4, 223-230 (1996)
    [DOI: 10.1016/0928-0987(95)00050-X] [PDF]
72. The effect of polyethylene glycol on the charcoal adsorption of chlorpromazine studied by ion selective electrode potentiometry
    J Atta-Politou, PE Macheras, MA Koupparis
    J. Toxicol.-Clin. Toxicol. 34, 307-316 (1996)
    [DOI: 10.3109/15563659609013795] [PDF]
73. Gastrointestinal Drug Absorption: Is It Time to Consider Heterogeneity as Well as Homogeneity?
    Panos Macheras and Panos Argyrakis
    Pharm. Res. 14, 842-847 (1997)
    [DOI: 10.1023/A:1012183313218] [PDF]
74. A population growth model of dissolution
    A Dokoumetzidis, P Macheras
    Pharm. Res. 14, 1122-1126 (1997)
    [DOI: 10.1023/A:1012182102257] [PDF]
75. Effect of elevated viscosity in the upper gastrointestinal tract on drug absorption in dogs
    C Reppas, G Eleftheriou, P Macheras, M Symillides, JB Dressman
    Eur. J. Pharm. Sci. 6, 131-139 (1998)
    [DOI: 10.1016/S0928-0987(97)00077-8] [PDF]
76. Investigation of absorption kinetics by the phase plane method
    A Dokoumetzidis, P Macheras
    Pharm. Res. 15, 1262-1269 (1998)
    [DOI: 10.1023/A:1011952227079] [PDF]
77. The effect of HPMC - a cholesterol-lowering agent - on oral drug absorption in dogs
    C Reppas, G Eleftheriou, P Macheras, M Symillides, D Greenwood, JB Dressman
    Biopharm. Drug Dispos. 19, 523-530 (1998)
    [DOI: 10.1002/(SICI)1099-081X(1998110)19:8<523::AID-BDD133>3.0.CO;2-J] [PDF]
78. An alternative method for the estimation of the terminal slope when a few data points are available
    Aristides Dokoumetzidis, Athanassios Iliadis, and Panos Macheras
    J. Pharm. Sci. 88, 557-560 (1999)
    [DOI: 10.1021/js980317l] [PDF]
79. Heterogeneous tube model for the study of small intestinal transit flow
    A Kalampokis, P Argyrakis, P Macheras
    Pharm. Res. 16, 87-91 (1999)
    [DOI: 10.1023/A:1018874913372] [PDF]
80. Quantitative determination of cefepime in plasma and vitreous fluid by high-performance liquid chromatography
    IN Valassis, M Parissi-Poulou, P Macheras
    J. Chromatogr. B 721, 249-255 (1999)
    [DOI: 10.1016/S0378-4347(98)00468-X] [PDF]
81. Modeling of supersaturated dissolution data
    G Valsami, A Dokoumetzidis, P Macheras
    Int. J. Pharm. 181, 153-157 (1999)
    [DOI: 10.1016/S0378-5173(99)00020-4] [PDF]
82. A heterogeneous tube model of intestinal drug absorption based on probabilistic concepts
    A Kalampokis, P Argyrakis, P Macheras
    Pharm. Res. 16, 1764-1769 (1999)
    [DOI: 10.1023/A:1018918402237] [PDF]
83. A displacement approach for competitive drug-protein binding studies using the potentiometric 1-anilino-8-naphthalene-sulfonate probe technique
    A Angelakou, G Valsami, P Macheras, M Koupparis
    Eur. J. Pharm. Sci. 9, 123-130 (1999)
    [DOI: 10.1016/S0928-0987(99)00036-6] [PDF]
84. Studies on the interaction of diflunisal ion with cyclodextrins using ion-selective electrode potentiometry
    EE Sideris, GN Valsami, MA Koupparis, PE Macheras
    Eur. J. Pharm. Sci. 7, 271-278 (1999)
    [DOI: 10.1016/S0928-0987(98)00035-9] [PDF]
85. On the heterogeneity of drug dissolution and release
    Panos Macheras & Aristides Dokoumetzidis
    Pharm. Res. 17, 108-112 (2000)
    [DOI: 10.1023/A:1007596709657] [PDF]
    Errata: On the heterogeneity of drug dissolution and release. (vol 17, pg 108, 2000)
    P Macheras, A Dokoumetzidis
    Pharm. Res. 18, 719 (2001)
    [DOI: 10.1023/A:1017304632432] [PDF]
86. Non-linear regression analysis with errors in both variables: Estimation of co-operative binding parameters
    G Valsami, A Iliadis, P Macheras
    Biopharm. Drug Dispos. 21, 7-14 (2000)
    [DOI: 10.1002/1099-081X(200001)21:1<7::AID-BDD210>3.0.CO;2-F] [PDF]
87. Cyclosporin a pharmacokinetics in liver transplant recipients effect of ursodeoxycholic acid.
    A Iliadis, P Macheras, FX Caroli-Bosc, AM Montet, L Salmon, JC Montet
    Gastroenterology 118, A984-A984 (2000)
    [DOI: 10.1016/S0016-5085(00)86082-5] [PDF]
88. On the use of partial AUC as an early exposure metric
    A Dokoumetzidis, P Macheras
    Eur. J. Pharm. Sci. 10, 91-95 (2000)
    [DOI: 10.1016/S0928-0987(99)00095-0] [PDF]
89. Ursodeoxycholic acid modulates cyclosporin A oral absorption in liver transplant recipients
    FX Caroli-Bose, A Iliadis, L Salmon, P Macheras, AM Montet, A Bourgeon, R Garraffo, JP Delmont, JC Montet
    Fundam. Clin. Pharmacol. 14, 601-609 (2000)
    [DOI: 10.1111/j.1472-8206.2000.tb00446.x] [PDF]
90. Nonlinear Dynamics and Chaos Theory: Concepts and Applications Relevant to Pharmacodynamics
    Aristides Dokoumetzidis, Athanassios Iliadis, and Panos Macheras
    Pharm. Res. 18, 415-426 (2001)
    [DOI: 10.1023/A:1011083723190] [PDF]
91. A Stochastic Model Describes the Heterogeneous Pharmacokinetics of Cyclosporin
    Laurent Claret, Athanassios Iliadis, and Panos Macheras
    J. Pharmacokinet. Pharmacodyn. 28, 445-463 (2001)
    [DOI: 10.1023/A:1012295014352] [PDF]
92. Fractal volume of drug distribution: It scales proportionally to body mass
    V Karalis, L Claret, A Iliadis, P Macheras
    Pharm. Res. 18, 1056-1060 (2001)
    [DOI: 10.1023/A:1010965001162] [PDF]
93. Drug disposition viewed in terms of the fractal volume of distribution
    V Karalis, P Macheras
    Pharm. Res. 19, 697-704 (2002)
    [DOI: 10.1023/A:1015378701592] [PDF]
94. Multivariate Statistics of Disposition Pharmacokinetic Parameters for Structurally Unrelated Drugs Used in Therapeutics
    Vangelis Karalis, Anna Tsantili-Kakoulidou, and Panos Macheras
    Pharm. Res. 19, 1827-1834 (2002)
    [DOI: 10.1023/A:1021489323828] [PDF]
95. Nonlinear dynamics in Clinical Pharmacology: the paradigm of cortisol secretion and suppression
    A Dokoumetzidis, A Iliadis, P Macheras
    Br. J. Clin. Pharmacol. 54, 21-29 (2002)
    [DOI: 10.1046/j.1365-2125.2002.01600.x] [PDF]
96. In silico prediction of ADME and pharmacokinetics - Report of an expert meeting organised by COST B15
    A Boobis, U Gundert-Remy, P Kremers, P Macheras, O Pelkonen
    Eur. J. Pharm. Sci. 17, 183-193 (2002)
    [DOI: 10.1016/S0928-0987(02)00185-9] [PDF]
97. Fractal kinetics in drug release from finite fractal matrices
    K. Kosmidis, P. Argyrakis and P. Macheras
    J. Chem. Phys. 119, 6373-7377 (2003)
    [DOI: 10.1063/1.1603731] [PDF]
98. The mean dissolution time depends on the dose/solubility ratio
    E Rinaki, A Dokoumetzidis, P Macheras
    Pharm. Res. 20, 406-408 (2003)
    [DOI: 10.1023/A:1022652004114] [PDF]
99. A reappraisal of drug release laws using Monte Carlo simulations: the prevalence of the Weibull function
    Kosmas Kosmidis, Panos Argyrakis, and Panos Macheras
    Pharm. Res. 20, 988-995 (2003)
    [DOI: 10.1023/A:1024497920145] [PDF]
100. Quantitative Biopharmaceutics Classification System: The Central Role of Dose/Solubility Ratio
     Eleni Rinaki, Georgia Valsami, and Panos Macheras
     Pharm. Res. 20, 1917-1925 (2003)
     [DOI: 10.1023/B:PHAM.0000008037.57884.11] [PDF]
101. The power law can describe the 'entire' drug release curvefrom HPMC-based matrix tablets: a hypothesis
     E. Rinaki, G. Valsami, P. Macheras
     Int. J. Pharm. 255, 199-207 (2003)
     [DOI: 10.1016/S0378-5173(03)00079-6] [PDF]
102. A model for transport and dispersion in the circulatory system based on the vascular fractal tree
     A Dokoumetzidis, P Macheras
     Ann. Biomed. Eng. 31, 284-293 (2003)
     [DOI: 10.1114/1.1555627] [PDF]
103. Analysis of Case II drug transport with radial and axial release from cylinders
     K Kosmidis, E Rinaki, P Argyrakis, P Macheras
     Int. J. Pharm. 254, 183-188 (2003)
     [DOI: 10.1016/S0378-5173(03)00030-9] [PDF]
104. Pharmacodynamic considerations in bioequivalence assessment: comparison of novel and existing metrics
     V Karalis, P Macheras
     Eur. J. Pharm. Sci. 19, 45-56 (2003)
     [DOI: 10.1016/S0928-0987(03)00064-2] [PDF]
105. Quantitative structure-pharmacokinetic relationships for disposition parameters of cephalosporins
     V Karalis, A Tsantili-Kakoulidou, P Macheras
     Eur. J. Pharm. Sci. 20, 115-123 (2003)
     [DOI: 10.1016/S0928-0987(03)00177-5] [PDF]
106. Pharmacokinetic Strategies in Deciphering Atypical Drug Absorption Profiles
     Honghui Zhou
     J. Clin. Pharmacol. 43, 211-227 (2003)
     [DOI: 10.1177/0091270002250613] [PDF]
107. Population pharmacokinetic/pharmacodynamic methods and their application Population pharmacokinetic/pharmacodynamic methods and their application: an introduction<
     P. Macheras, J. Lukas.
     Pharmakeftiki 16, 65-68, (2003)
     
108. Identification of Biowaivers Among Class II Drugs: Theoretical Justification and Practical Examples
     Eleni Rinaki, Aristides Dokoumetzidis, Georgia Valsami, and Panos Macheras
     Pharm. Res. 21, 1567-1572 (2004)
     [DOI: 10.1023/B:PHAM.0000041450.25106.c8] [PDF]
109. A physiologically based approach for the estimation of recirculatory parameters
     V Karalis, A Dokoumetzidis, P Macheras
     J. Pharmacol. Exp. Ther. 308, 198-205 (2004)
     [DOI: 10.1124/jpet.103.058941] [PDF]
110. The heterogenous course of drug transit through the body
     A Dokoumetzidis, V Karalis, A Iliadis, P Macheras
     Trends Pharmacol. Sci. 25, 140-146 (2004)
     [DOI: 10.1016/j.tips.2004.01.008] [PDF]
111. Michaelis-Menten kinetics under spatially constrained conditions: Application to mibefradil pharmacokinetics
     K Kosmidis, V Karalis, P Argyrakis, P Macheras
     Biophys. J. 87, 1498-1506 (2004)
     [DOI: 10.1529/biophysj.104.042143] [PDF]
112. Novel scaled average bioequivalence limits based on GMR and variability considerations
     V Karalis, M Symillides, P Macheras
     Pharm. Res. 21, 1933-1942 (2004)
     [DOI: 10.1023/B:PHAM.0000045249.83899.ae] [PDF]
113. Pharmacokinetics of teicoplanin in an ICU population of children and infants
     JC Lukas, G Karikas, M Gazouli, P Kalabalikis, T Hatzis, P Macheras
     Pharm. Res. 21, 2064-2071 (2004)
     [DOI: 10.1023/B:PHAM.0000048198.56873.d8] [PDF]
114. Modeling and Monte Carlo simulations in oral drug absorption
     A Dokoumetzidis, K Kosmidis, P Argyrakis, P Macheras
     Basic Clin. Pharmacol. Toxicol. 96, 200-205 (2005)
     [DOI: 10.1111/j.1742-7843.2005.pto960309.x] [PDF]
115. Geometric mean ratio-dependent scaled bioequivalence limits with leveling-off properties
     V Karalis, P Macheras, M Symillides
     Eur. J. Pharm. Sci. 26, 54-61 (2005)
     [DOI: 10.1016/j.ejps.2005.04.019] [PDF]
116. Bicompartmental kinetics of tobramycin analysed with a wide range of covariates
     G Inclan, E Suarez, R Calvo, C Aguirre, P Macheras, M Gazouli, JC Lukas
     Int. J. Antimicrob. Agents 26, 304-311 (2005)
     [DOI: 10.1016/j.ijantimicag.2005.05.004] [PDF]
117. Analysis of Dissolution Data Using Modified Versions of Noyes-Whitney Equation and the Weibull Function
     Aristides Dokoumetzidis, Vasiliki Papadopoulou & Panos Macheras
     Pharm. Res. 23, 256-261 (2006)
     [DOI: 10.1007/s11095-006-9093-3] [PDF]
118. On the use of the Weibull function for the discernment of drug release mechanisms
     Vasiliki Papadopoulou, Kosmas Kosmidis, Marilena Vlachou, Panos Macheras
     Int. J. Pharm. 309, 44-50 (2006)
     [DOI: 10.1016/j.ijpharm.2005.10.044] [PDF]
119. A century of dissolution research: From Noyes and Whitney to the Biopharmaceutics Classification System
     Aristides Dokoumetzidis, Panos Macheras
     Int. J. Pharm. 321, 1-11 (2006)
     [DOI: 10.1016/j.ijpharm.2006.07.011] [PDF]
120. In-vitro study on the competitive binding of diflunisal and uraemic toxins to serum albumin and human plasma using a potentiometric ion-probe technique
     A. Davilas, M. Koupparis, P. Macheras, G. Valsami
     J. Pharm. Pharmacol. 58, 1467-1474 (2006)
     [DOI: 10.1211/jpp.58.11.0007] [PDF]
121. A comment on "adverse drug reactions and avalanches: Life at the edge of chaos"
     Aristides Dokoumetzidis, Panos Macheras
     J. Clin. Pharmacol. 46, 1057-1058 (2006)
     [DOI: 10.1177/0091270006291620] [PDF]
122. Novel scaled bioequivalence limits with leveling-off properties
     John Kytariolos, Vangelis Karalis, Panos Macheras, Mira Symillides
     Pharm. Res. 23, 2657-2664 (2006)
     [DOI: 10.1007/s11095-006-9107-1] [PDF]
123. Advanced pharmacokinetic models based on organ clearance, circulatory, and fractal concepts
     K. Sandy Pang, Michael Weiss, and Panos Macheras
     APPS J. 9, E268-E283 (2007)
     [DOI: 10.1208/aapsj0902030] [PDF]
124. Modelling and simulation in drug absorption processes
     A. Dokoumetzidis, G. Valsami, P. Macheras
     Xenobiotica 37, 1052-1065 (2007)
     [DOI: 10.1080/00498250701502114] [PDF]
125. Monte Carlo simulations for the study of drug release from matrices with high and low diffusivity areas
     Kosmas Kosmidis, Panos Macheras
     Int. J. Pharm. 343, 166-172 (2007)
     [DOI: 10.1016/j.ijpharm.2007.05.021] [PDF]
126. IVIVC of controlled release formulations: Physiological-dynamical reasons for their failure
     A. Dokoumetzidis, P. Macheras
     J. Control. Release 129, 76-78 (2008)
     [DOI: 10.1016/j.jconrel.2008.04.005] [PDF]
127. Monte Carlo simulations of drug release from matrices with periodic layers of high and low diffusivity
     Kosmas Kosmidis, Panos Macheras
     Int. J. Pharm. 354, 111-116 (2008)
     [DOI: 10.1016/j.ijpharm.2007.10.036] [PDF]
128. Development of a reaction-limited model of dissolution: Application to official dissolution tests experiments
     A. Dokoumetzidis, V. Papadopoulou, G. Valsami, P. Macheras
     Int. J. Pharm. 355, 114-125 (2008)
     [DOI: 10.1016/j.ijpharm.2007.11.056] [PDF]
129. Biopharmaceutics classification systems for new molecular entities (BCS-NMEs) and marketed drugs (BCS-MD): Theoretical basis and practical examples
     Vasiliki Papadopoulou, Georgia Valsami, Aristides Dokoumetzidis, Panos Macheras
     Int. J. Pharm. 361, 70-77 (2008)
     [DOI: 10.1016/j.ijpharm.2008.05.021] [PDF]
130. Bioavailability and Bioequivalence: Focus on physiological factors and variability
     Vangelis Karalis, Panos Macheras, Achiel Van Peer, Vinod P. Shah
     Pharm. Res. 25, 1956-1962 (2008)
     [DOI: 10.1007/s11095-008-9645-9] [PDF]
131. Fractional kinetics in drug absorption and disposition processes
     Aristides Dokoumetzidis and Panos Macheras
     J. Pharmacokinet. Pharmacodyn. 36, 165-178 (2009)
     [DOI: 10.1007/s10928-009-9116-x] [PDF]
132. Comparison of the reference scaled bioequivalence semi-replicate method with other approaches: Focus on human exposure to drugs
     Vangelis Karalis, Mira Symillides, Panos Macheras
     Eur. J. Pharm. Sci. 38, 55-63 (2009)
     [DOI: 10.1016/j.ejps.2009.05.013] [PDF]
133. Physiologically-Based PK/PD Modelling of Therapeutic Macromolecules
     Peter Thygesen, Panos Macheras, Achiel Van Peer
     Pharm. Res. 26, 2543-2550 (2009)
     [DOI: 10.1007/s11095-009-9990-3] [PDF]
134. Effect of Cyclodextrin Complexation on the Aqueous Solubility and Solubility/Dose Ratio of Praziquantel
     Stratos Maragos, Helen Archontaki, Panos Macheras, Georgia Valsami
     AAPS PharmSciTech 10, 1444-1451 (2009)
     [DOI: 10.1208/s12249-009-9346-7] [PDF]
135. Pharmacogenetics in individualized therapy for brain cancer patients
     E. Magklara, I. Vizirianakis, P. Macheras.
     Pharmakeftiki 22, 117-123 (2009)
     
136. Novel milk-based oral formulations: Proof of concept
     Georgia Charkoftaki, John Kytariolos, Panos Macheras
     Int. J. Pharm. 390, 150-159 (2010)
     [DOI: 10.1016/j.ijpharm.2010.001.038] [PDF]
137. A commentary on fractionalization of multi-compartmental models
     Aristides Dokoumetzidis, Richard Magin, Panos Macheras
     J. Pharmacokinet. Pharmacodyn. 37, 203-207 (2010)
     [DOI: 10.1007/s10928-010-9153-5] [PDF]
138. Fractional kinetics in multi-compartmental systems
     Aristides Dokoumetzidis, Richard Magin, Panos Macheras
     J. Pharmacokinet. Pharmacodyn. 37, 507-524 (2010)
     [DOI: 10.1007/s10928-010-9170-4] [PDF]
139. Examining the Role of Metabolites in Bioequivalence Assessment
     Vangelis Karalis, Panos Macheras
     J. Pharm. Pharmaceut. Sci. 13, 198-217 (2010)
     [DOI: 10.18433/J35889] [PDF]
140. Biopharmaceutical Classification Based on Solubility and Dissolution: A Reappraisal of Criteria for Hypothesis Models in the Light of the Experimental Observations
     Georgia Charkoftaki, Aristides Dokoumetzidis, Georgia Valsami, Panos Macheras
     Basic Clin. Pharmacol. Toxicol. 106, 168-172 (2010)
     [DOI: 10.1111/j.1742-7843.2009.00506.x] [PDF]
141. Power law IVIVC: An application of fractional kinetics for drug release and absorption
     John Kytariolos, Aristides Dokoumetzidis, Panos Macheras
     Eur. J. Pharm. Sci. 41, 299-304 (2010)
     [DOI: 10.1016/j.ejps.2010.06.015] [PDF]
142. From drug delivery systems to drug release, dissolution IVIVC, BCS, BDDCS, bioequivalence and biowaivers
     V. Karalis, E. Magklara, V. Shah, P. Macheras
     Pharmaceutical Research. 27, 2018-2029 (2010)
     
143. Computational-Regulatory Developments in the Prediction of Oral Drug Absorption
     G. Valsami, P. Macheras
     Mol. Inf. 30, 112-121 (2011)
     [DOI: 10.1002/minf.201000171] [PDF]
144. Novel methods to assess bioequivalence
     Vangelis Karalis, Mira Symillides, Panos Macheras
     Expert Opin. Drug Metab. Toxicol. 7, 79-88 (2011)
     [DOI: 10.1517/17425255.2011.539202] [PDF]
145. Supersaturated dissolution data and their interpretation: the TPGS-carbamazepine model case
     Georgia Charkoftaki, Aristides Dokoumetzidis, Georgia Valsami, Panos Macheras
     J. Pharm. Pharmacol. 63, 352-361 (2011)
     [DOI: 10.1111/j.2042-7158.2010.01226.x] [PDF]
146. The Changing Face of the Rate Concept in Biopharmaceutical Sciences: From Classical to Fractal and Finally to Fractional
     Aristides Dokoumetzidis, Panos Macheras
     Pharm. Res. 28, 1229-1232 (2011)
     [DOI: 10.1007/s11095-011-0370-4] [PDF]
147. From the Higuchi Law and the linear ivivc to fractional kinetics and the nonlinear ivivc
     Aristides Dokoumetzidis, Panos Macheras
     Eur. J. Pharm. Sci. 44, Supplement 1, 17 (2011) [Proceedings of "4th BBBB International Conference on Pharmaceutical Sciences"]
     [Source: ScienceDirect]
148. Monte Carlo simulations and fractional kinetics considerations for the Higuchi equation
     Aristides Dokoumetzidis, Kosmas Kosmidis, Panos Macheras
     Int. J. Pharm. 418, 100-103 (2011)
     [DOI: 10.1016/j.ijpharm.2010.11.046] [PDF]
149. On the leveling-off properties of the new bioequivalence limits for highly variable drugs of the EMA guideline
     Vangelis Karalis, Mira Symillides, Panos Macheras
     Eur. J. Pharm. Sci. 44, 497-505 (2011)
     [DOI: 10.1016/j.ejps.2011.09.008] [PDF]
150. From Supersaturated Drug Delivery Systems to the Rising Era of Pediatric Formulations
     G. Charkoftaki, G. Valsami, P. Macheras
     Chem. Biochem. Eng. Q. 26, 427-434 (2012)
     [DOI: 10.15255/CABEQ.2014.119]
151. Bioequivalence of Highly Variable Drugs: A Comparison of the Newly Proposed Regulatory Approaches by FDA and EMA
     Vangelis Karalis, Mira Symillides, Panos Macheras
     Pharm. Res. 29, 1066-1077 (2012)
     [DOI: 10.1007/s11095-011-0651-y] [PDF]
152. Current regulatory approaches of bioequivalence testing
     Vangelis Karalis, Panos Macheras
     Expert Opin. Drug Metab. Toxicol. 8, 929-942 (2012)
     [DOI: 10.1517/17425255.2012.690394] [PDF]
153. Elucidating the Role of Dose in the Biopharmaceutics Classification of Drugs: The Concepts of Critical Dose, Effective In Vivo Solubility, and Dose-Dependent BCS
     Georgia Charkoftaki, Aristides Dokoumetzidis, Georgia Valsami, Panos Macheras
     Pharm. Res. 29, 3188-3198 (2012)
     [DOI: 10.1007/s11095-012-0815-4] [PDF]
154. Medication for the treatment of lung cancer: Emphasis on aerosolized chemotherapy
     K. Soulele, E. Christodoulou, P. Macheras.
     Pneumon 25, 298-304 (2012)
     
155. Stability and physicochemical characterization of novel milk-based oral formulations
     J. Kytariolos, G. Charkoftaki, J. R. Smith, G. Voyiatzis, A. Chrissanthopoulos, S. N. Yannopoulos, D. G. Fatouros, P. Macheras
     Int. J. Pharm. 444, 128-138 (2013)
     [DOI: 10.1016/j.ijpharm.2013.01.022] [PDF]
156. Exploring the Relationships Between Scaled Bioequivalence Limits and Within-Subject Variability
     Mira Symillides, Vangelis Karalis, Panos Macheras
     J. Pharm. Sci. 102, 297-301 (2013)
     [DOI: 10.1002/jps.23365] [PDF]
157. An Insight into the Properties of a Two-Stage Design in Bioequivalence Studies
     Vangelis Karalis, Panos Macheras
     Pharm. Res. 30, 1824-1835 (2013)
     [DOI: 10.1007/s11095-013-1026-3] [PDF]
158. Keeping a Critical Eye on the Science and the Regulation of Oral Drug Absorption: A Review
     Panos Macheras, Vangelis Karalis, Georgia Valsami
     J. Pharm. Sci. 102, 3018-3036 (2013)
     [DOI: 10.1002/jps.23534] [PDF]
159. A Report from the Pediatric Formulations Task Force: Perspectives on the State of Child-Friendly Oral Dosage Forms
     Anne Zajicek, Michael J. Fossler, Jeffrey S. Barrett, Jeffrey H. Worthington, Robert Ternik, Georgia Charkoftaki, Susan Lum, Joerg Breitkreutz, Mike Baltezor, Panos Macheras, Mansoor Khan, Shreeram Agharkar, David Douglas MacLaren
     AAPS J. 15, 1072-1081 (2013)
     [DOI: 10.1208/s12248-013-9511-5] [PDF]
160. On the ubiquitous presence of fractals and fractal concepts in pharmaceutical sciences: A review
     Natassa Pippa, Aristides Dokoumetzidis, Costas Demetzos, Panos Macheras
     Int. J. Pharm. 456, 340-352 (2013)
     [DOI: 10.1016/j.ijpharm.2013.08.087] [PDF]
161. Quantitative assessment of the switchability of generic products
     Vangelis Karalis, Meir Bialer, Panos Macheras
     Eur. J. Pharm. Sci. 50, 476-483 (2013)
     [DOI: 10.1016/j.ejps.2013.08.023] [PDF]
162. A non-binary biopharmaceutical classification of drugs: The ABΓ system
     Panos Macheras, Vangelis Karalis
     Int. J. Pharm. 464, 85-90 (2014)
     [DOI: 10.1016/j.ijpharm.2014.01.022] [PDF]
163. On the statistical model of the two-stage designs in bioequivalence assessment
     Vangelis Karalis, Panos Macheras
     J. Pharm. Pharmacol. 66, 48-52 (2014)
     [DOI: 10.1111/jphp.12164] [PDF]
164. Generic Products of Antiepileptic Drugs: A Perspective on Bioequivalence, Bioavailability, and Formulation Switches Using Monte Carlo Simulations
     Vangelis Karalis, Panos Macheras, Meir Bialer
     CNS Drugs 28, 69-77 (2014)
     [DOI: 10.1007/s40263-013-0112-8] [PDF]
165. Comment and reply on: A randomized crossover trial investigating the ease of use and preference of two dry powder inhalers in patients with asthma of chronic obstructive pulmonary disease
     Panos Macheras
     Expert Opin. Drug Deliv. 11, 823-824 (2014)
     [DOI: 10.1517/17425247.2014.889648] [PDF]
166. Population pharmacokinetics of fluticasone propionate/salmeterol using two different dry powder inhalers
     K. Soulele, P. Macheras, L. Silvestro, S. Rizea Savu, V. Karalis
     Eur. J. Pharm. Sci. 80, 33-42 (2015)
     [DOI: 10.1016/j.ejps.2015.08.009] [PDF]
167. Scientific considerations concerning the EMA change in the definition of "dose" of the BCS-based biowaiver guideline and implications for bioequivalence
     Chrysa Daousani, Panos Macheras
     Int. J. Pharm. 478, 606-609 (2015)
     [DOI: 10.1016/j.ijpharm.2014.11.062] [PDF]
168. Milk as a medium for pediatric formulations: Experimental findings and regulatory aspects
     Konstantina Soulele, Panos Macheras
     Int. J. Pharm. 492, 344-345 (2015)
     [DOI: 10.1016/j.ijpharm.2015.05.015] [PDF]
169. Biopharmaceutic classification of drugs revisited
     Chrysa Daousani, Panos Macheras
     Eur. J. Pharm. Sci. 95, 82-87 (2016)
     [DOI: 10.1016/j.ejps.2016.08.001] [PDF]
170. Pharmacokinetic analysis of inhaled salmeterol in asthma patients: Evidence from two dry powder inhalers
     Konstantina Soulele, Panos Macheras, Vangelis Karalis
     Biopharm. Drug Disp. 38, 407-419 (2017)
     [DOI: 10.1002/bdd.2077] [PDF]
171. Modeling and administration scheduling of fractional-order pharmacokinetic systems
     Domagoj Herceg, Sotiris Ntouskas, Pantelis Sopasakis, Aris Dokoumetzidis, Panos Macheras, Haralambos Sarimveis, Panagiotis Patrinos
     IFAC PAPERSONLINE 50, 9742-9747 (2017)
     [DOI: 10.1016/j.ifacol.2017.08.2178] [PDF]
172. On the pharmacokinetics of two inhaled budesonide/formoterol combinations in asthma patients using modeling approaches
     K. Soulele, P. Macheras, V. Karalis
     Pulmonary Pharmacology and Therauptics 48, 168-178 (2018)
     [DOI: 10.1016/j.pupt.2017.12.002] [PDF]
173. On the dilemma of fractal or fractional kinetics in drug release studies: A comparison between Weibull and Mittag-Leffler functions
     Kosmas Kosmidis, Panos Macheras
     Int. J. Pharm. 543, 269-273 (2018)
     [DOI: 10.1016/j.ijpharm.2018.03.060] [PDF]
174. Fractional calculus in pharmacokinetics
     Pantelis Sopasakis, Haralambos Sarimveis, Panos Macheras, Aristides Dokoumetzidis
     J. Pharmacokinet. Pharmacodyn. 45, 107-125 (2018)
     [DOI: 10.1007/s10928-017-9547-8] [PDF]
175. A reaction limited in vivo dissolution model for the study of drug absorption: Towards a new paradigm for the biopharmaceutic classification of drugs
     Panos Macheras, Athanassios Iliadis, Georgia Melagraki
     Eur. J. Pharm. Sci. 117, 98-106 (2018)
     [DOI: 10.1016/j.ejps.2018.02.003] [PDF]
176. On the unphysical hypotheses in pharmacokinetics and oral drug absorption: Time to utilize instantaneous rate coefficients instead of rate constants
     Panteleimon D. Mavroudis, Kosmas Kosmidis, Panos Macheras
     Eur. J. Pharm. Sci. 130, 137-146 (2019)
     [DOI: 10.1016/j.ejps.2019.01.027] [PDF]
177. On an Unphysical Hypothesis of Bateman Equation and its Implications for Pharmacokinetics
     Panos Macheras
     Pharm. Res. 36, 94 (2019)
     [DOI: 10.1007/s11095-019-2633-4] [PDF]
178. The Biopharmaceutics Classification System (BCS) and the Biopharmaceutics Drug Disposition Classification System (BDDCS)_ Beyond guidelines
     Aggelos Charalabidis, Maria Sfouni, Christel Bergström, Panos Macheras
     Int. J. Pharm. 566, 264-281 (2019)
     [DOI: 10.1016/j.ijpharm.2019.05.041] [PDF]
179. Revising Pharmacokinetics of Oral Drug Absorption: I Models Based on Biopharmaceutical/Physiological and Finite Absorption Time Concepts
     Panos Macheras, Pavlos Chryssafidis
     Pharm. Res. 37, 187 (2020)
     [DOI: 10.1007/s11095-020-02894-w] [PDF]
     Correction to: Revising Pharmacokinetics of Oral Drug Absorption: I Models Based on Biopharmaceutical/Physiological and Finite Absorption Time Concepts
     Panos Macheras, Pavlos Chryssafidis
     Pharm. Res. 37, 206 (2020)
     [DOI: 10.1007/s11095-020-02935-4] [PDF]
180. A fractal kinetics SI model can explain the dynamics of COVID-19 epidemics
     Kosmas Kosmidis, Panos Macheras
     PLOS One 15, e0237304 (2020)
     [DOI: 10.1371/journal.pone.0237304] [PDF]
181. Demystifying the spreading of pandemics I: The fractal kinetics SI model quantifies the dynamics of COVID-19
     Panos Macheras, Kosmas Kosmidis, Pavlos Chryssafidis
     meRxiv (2020)
     [DOI: 10.1101/2020.11.15.20232132] [PDF]
182. Interpreting airborne pandemics spreading using fractal kinetics' principles
     P. Macheras, A. A. Tsekouras, and P. Chryssafidis
     F1000Research 10, 609 (2021)
     [DOI: 10.12688/f1000research.53196.1] [PDF]
183. Revising Pharmacokinetics of Oral Drug Absorption: II Bioavailability-Bioequivalence Considerations
     Pavlos Chryssafidis, Athanasios A. Tsekouras, Panos Macheras
     Pharm. Res. 38, 1345-1356 (2021)
     [DOI: 10.1007/s11095-021-03078-w] [PDF]
     Correction to: Revising Pharmacokinetics of Oral Drug Absorption: II Bioavailability-Bioequivalence Considerations
     Pavlos Chryssafidis, Athanasios A. Tsekouras, Panos Macheras
     Pharm. Res. 38, 1633 (2021)
     [DOI: 10.1007/s11095-021-03101-0] [PDF]
184. Enhancement of Docetaxel Absorption Using Ritonavir in an Oral Milk-Based Formulation
     K. Soulele, T. Karampelas, C. Tamvakopoulos, P. Macheras
     Pharm. Res. 38, 1419-1428 (2021)
     [DOI: 10.1007/s11095-021-03085-x] [PDF]
185. Re-examining digoxin bioavailability after half a century: Time for changes in the bioavailability concepts
     Athanasios A. Tsekouras, Panos Macheras
     Pharm. Res. 38, 1635-1638 (2021)
     [DOI: 10.1007/s11095-021-03121-w] [PDF]
     Correction to: Re-examining digoxin bioavailability after half a century: Time for changes in the bioavailability concepts
     Athanasios A. Tsekouras, Panos Macheras
     Pharm. Res. 38, 2185 (2021)
     [DOI: 10.1007/s11095-021-03148-z] [PDF]
186. Drugs are Absorbed in Finite Time: A New Era in Biopharmaceutics and Pharmacokinetics
     P. Macheras
     Acta Pharmaceutica Hungarica. 85, 148-149 (2021)
     [DOI: 10.33892/aph.2021.91.148-149]
187. Re-writing oral pharmacokinetics using physiologically based finite time pharmacokinetic (PBFTPK) models
     P. Chryssafidis, A. A. Tsekouras, P. Macheras
     Pharm. Res. 39, 691-701 (2022)
     [DOI: 10.1007/s11095-022-03230-0] [PDF]
188. From Camille Nούς to Apollonian and the Dionysian scientists
     Panos Macheras, Caitlin Di Paolo, Yanna Pusica and Eleftherios P. Diamandis
     Diagnosis 9, 1-2 (2022)
     [DOI: 10.1515/dx-2021-0057] [PDF]
189. Columbus' egg: Oral drugs are absorbed in finite time
     P. Macheras, A. A. Tsekouras
     Eur. J. Pharm. Sci. 176, 106265 (2022)
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Interesting links

• ClinicalTrials.gov: Clinical Study to Investigate the Pharmacokinetics of Multiple Repeated Doses of Intranasal Naloxone (FDA/Spaulding Clinical Research LLC)
• FDA. Bioavailability and Bioequivalence Studies Submitted in NDAs or INDs - General Considerations (2014) [https://www.gmp-compliance.org/files/guidemgr/UCM389370.pdf] [also here]
• EMA ICH M9 guideline on biopharmaceutics classification system-based biowaivers Step 5 [also here]
• EMA, CHMP: Guideline on the investigation of bioequivalence (2010) [also here]
• EMA: Draft on AI in the medicinal product lifecycle (2023) [also here]
• Waiver of In Vivo Bioavailability and Bioequivalence Studies for Immediate-Release Solid Oral Dosage Forms Based on a Biopharmaceutics Classification System Guidance for Industry by FDA/CDER/ Purdie, Florine P [also here]
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