G. Kokotos: Publications

1. Synthesis and study of substituted coumarins - A facile preparation of d,l-o-tyrosine
   Kokotos G, Tzougraki C
   J Heterocyclic Chem 23 (1): 87-92 JAN-FEB 1986
2. Fluorogenic substrates for chymotrypsin with new fluorescent markers
   Kokotos G, Tzougraki C
   Int J Pept Prot Res 28 (2): 186-191 AUG 1986
3. Synthesis and use of an aminoquinolinone derivative for the fluorometric-determination of oxytocinase
   Maskova HP, Kokotos G, Tzougraki C, Barth T
   Collect Czech Chem C 54 (10): 2802-2808 OCT 1989
4. A convenient one-pot conversion of N-protected amino-acids and peptides into alcohols
   Kokotos G
   Synthesis-Stuttgart (4): 299-301 APR 1990
5. New fluorogenic substrates for the determination of postproline endopeptidase activity
   Tzougraki C, Kokotos G, Maskova HP, Anzenbacherova E, Barth T
   Collect Czech Chem C 55 (4): 1112-1118 APR 1990
6. Fluorogenic substrates for chymotrypsin with 2-quinolinone derivatives as leaving groups
   Kokotos G, Geiger R, Tzougraki C
   Biol Chem H-S 371 (9): 835-840 SEP 1990
7. Products from furans .13. Synthesis of 6-acyloxy and 6-alkoxy derivatives of 2H-pyran-3(6H)-ones
   Constantinou-Kokotou V, Kokotos G, Georgiadis MP
   Liebigs Ann Chem (2): 151-154 FEB 1991
8. Synthesis and study of intramolecularly-quenched fluorogenic substrates containing aminocoumarin or aminoquinolinone-type fluorophores
   Kokotos G, Tzougraki C
   J Chem Soc Perk T 2 (4): 495-499 APR 1991
9. Synthesis of amino-acid derivatives of neamine and 2-deoxystreptamine to be used as mutasynthons
   Georgiadis MP, Constantinou-Kokotou V, Kokotos G
   J Carbohyd Chem 10 (5): 739-748 1991
10. Products from furans .12. Resolution of 2,3-dideoxy-dl-2-enopyranos-4-uloses via chromatographic-separation of their diastereomeric 0-tert-butyloxycarbonyl-l-alanyl esters - A convenient synthesis of l-aculose and d-aculose
    Constantinou-Kokotou V, Couladouros EA, Georgiadis MP, Kokotos G
    J Carbohyd Chem 10 (5): 749-756 1991
11. Products from furans .11. Total synthesis of 4-(d-alanylamino)-2-amino-2,3,4-trideoxy-dl-threo-pentose (3-deoxy-dl-prumycin)
    Constantinou-Kokotou V, Couladouros EA, Georgiadis MP, Kokotos G, Georgiadis TM
    Carbohyd Res 222: 163-172 DEC 30 1991
12. Lipidic peptides .14. conversion of racemic lipidic amino-acids into sphingosine and ceramide analogs and 1,2-diamines
    Kokotos G, Constantinou-Kokotou V, Fernandez ED, Toth I, Gibbons WA
    Liebigs Ann Chem (9): 961-964 SEP 1992
13. Modified amino-acids and peptides .2. A convenient conversion of amino and peptide alcohols into amines
    Kokotos G, Constantinou-Kokotou V
    J Chem Res-S (12): 391-391 DEC 1992
14. A synthesis in one reaction vessel of 2,4-diamino sugar precursors from 2,3-dideoxy-2-enopyranos-4-uloses
    Couladouros EA, Constantinou-Kokotou V, Georgiadis MP, Kokotos G
    Carbohyd Res 254: 317-324 FEB 17 1994
15. Fluorogenic substrates containing 7-amino-4-methyl-2-quinolinone for aminopeptidase-m, chymotrypsin, elastase and trypsin, determination of enzyme-activity
    Tzougraki C, Noula C, Geiger R, Kokotos G
    Liebigs Ann Chem (4): 365-368 APR 1994
16. Synthesis and antifungal activity of 3-deoxy-dl-prumycin analogs
    Constantinou-Kokotou V, Kokotos G, Chrysayito-Kousbalides M, Couladouros EA, Georgiadis MP
    Liebigs Ann Chem (8): 847-850 AUG 1994
17. Synthesis of 1,3-diamines
    Constantinou-Kokotou V, Kokotos G
    Org Prep Proced Int 26 (5): 599-602 OCT 1994
18. Lipidic mimetics as inhibitors of pancreatic phospholipase A(2)
    Nicolaou A, Kokotos G, Constantinou V, York J, Gibbons WA
    BIOCHEM SOC T 23 (4): S614-S614 NOV 1995
19. A general approach to the enantiomeric synthesis of lipidic alpha-amino acids, peptides and vicinal amino alcohols
    Kokotos G, Padron JM, Noula C, Gibbons WA, Martin VS
    TETRAHEDRON-ASYMMETR 7 (3): 857-866 MAR 1996
20. Synthesis of lipidic amino acid and dipeptide inhibitors of human platelet phospholipase A(2)
    Kokotos G, Constantinou-Kokotou V, Noula C, Nicolaou A, Gibbons WA
    INT J PEPT PROT RES 48 (2): 160-166 AUG 1996
21. Selective one-pot conversion of carboxylic acids into alcohols
    Kokotos G, Noula C
    J ORG CHEM 61 (20): 6994-6996 OCT 4 1996
22. Synthesis of chiral triamines and diamines from amino acids
    Kokotos G, Markidis T, Constantinou-Kokotou V
    SYNTHESIS-STUTTGART (10): 1223-& OCT 1996
23. Synthesis of medicinally useful lipidic alpha-amino acids, 2-amino alcohols and diamines
    Kokotos G, Martin V, Constantinou-Kokotou V, Gibbons WA
    AMINO ACIDS 11 (3-4): 329-343 1996
24. Convenient synthesis of benzyl and allyl esters using benzyl and allyl 2,2,2-trichloroacetimidate
    Kokotos G, Chiou A
    SYNTHESIS-STUTTGART (2): 168-& FEB 1997
25. New fluorogenic substrates for the study of secondary specificity of prolyl oligopeptidase
    Noula C, Kokotos G, Barth T, Tzougraki C
    J PEPT RES 49 (1): 46-51 JAN 1997
26. An HPLC method for the measurement of polyamines and lipidic amines binding to DNA
    Karikas GA, ConstantinouKokotou V, Kokotos G
    J LIQ CHROMATOGR R T 20 (11): 1789-1796 1997
27. Stoichiometric measurement of DNA damage caused by 8-methoxy-psoralen and UVA
    Karikas GA, Schulpis KH, Kokotos G, Michas T, Georgala S
    CLIN BIOCHEM 30 (5): 439-442 JUL 1997
28. Synthesis and in vitro cytotoxicity of aminocoumarin platinum(II) complexes
    Kokotos G, Theodorou V, Tzougraki C, Deforce DLD, VandenEeckhout EG
    BIOORG MED CHEM LETT 7 (17): 2165-2168 SEP 9 1997
29. Synthesis and properties of novel lipopeptides and lipid mimetics
    Nicolau A, Kokotos G, Constantinou-Kokotou V, Charitos C, Noula C, Verger R, Gibbons WA
    J PEPT SCI 3 (4): 291-298 JUL-AUG 1997
30. Direct molecular interaction of phenylalanine with DNA measured by reversed-phase HPLC
    Schulpis KH, Karikas GA, Kokotos G
    CLIN CHEM 44 (1): 178-179 JAN 1998
31. A general approach to the asymmetric synthesis of unsaturated lipidic alpha-amino acids. The first synthesis of alpha-aminoarachidonic acid
    Kokotos G, Padron JM, Martin T, Gibbons WA, Martin VS
    J ORG CHEM 63 (11): 3741-3744 MAY 29 1998
32. Synthesis and in vitro cytotoxicity of lipophilic platinum(II) complexes
    Kokotos G, Theodorou V, Constantinou-Kokotou V, Gibbons WA, Roussakis C
    BIOORG MED CHEM LETT 8 (12): 1525-1530 JUN 16 1998
33. Measurement of molecular interaction of aspartame and its metabolites with DNA
    Karikas GA, Schulpis KH, Reclos G, Kokotos G
    CLIN BIOCHEM 31 (5): 405-407 JUL 1998
34. Unsaturated lipidic alpha-amino acids derivatives, a novel class of antisignalling agents with cytotoxic activity in vitro
    Padron JM, Kokotos G, Markidis T, Peters GJ, Martin VS
    ANN ONCOL 9: 436 Suppl. 2 1998
35. Preparative capillary zone electrophoresis in combination with off-line graphite furnace atomic absorption for the analysis of DNA complexes formed by a new aminocoumarine platinum (II) compound
    Deforce DLD, Kokotos G, Esmans EL, De Leenheer A, Van den Eeckhout EG
    ELECTROPHORESIS 19 (14): 2454-2458 OCT 1998
36. Enantiospecific synthesis of alpha-amino acid semialdehydes: a key step for the synthesis of unnatural unsaturated and saturated alpha-amino acids
    Padron JM, Kokotos G, Martin T, Markidis T, Gibbons WA, Martin VS
    TETRAHEDRON-ASYMMETR 9 (19): 3381-3394 OCT 2 1998
37. Synthesis and in vitro cytotoxicity of lipidic alcohols and amines
    Constantinou-Kokotou V, Kokotos G, Roussakis C
    ANTICANCER RES 18 (5A): 3439-3442 SEP-OCT 1998
38. Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols
    Padron JM, Martin VS, Hadjipavlou-Litina D, Noula C, Constantinou-Kokotou V, Peters GJ, Kokotos G
    BIOORG MED CHEM LETT 9 (6): 821-826 MAR 22 1999
39. Synthetic routes to lipidic diamines and amino alcohols: A class of potential antiinflammatory agents
    Kokotos G, Constantinou-Kokotou V, Noula C, Hadjipavlou-Litina D
    LIPIDS 34 (3): 307-311 MAR 1999
40. Synthesis of optically active lipidic alpha-amino acids and lipidic 2-amino alcohols
    Constantinou-Kokotou V, Kokotos G
    AMINO ACIDS 16 (3-4): 273-285 1999
41. Synthesis and study of a lipophilic alpha-keto amide inhibitor of pancreatic lipase
    Chiou A, Markidis T, Constantinou-Kokotou V, Verger R, Kokotos G
    ORG LETT 2 (3): 347-350 FEB 10 2000
42. Study of DNA interactions with melphalan, busulphan, and analogues using an HPLC method
    Karikas A, Constantinou-Kokotou V, Magrioti V, Kokotos G
    J LIQ CHROMATOGR R T 23 (12): 1859-1864 2000
43. Synthesis of 2-oxo amide triacylglycerol analogues and study of their inhibition effect on pancreatic and gastric lipases
    Kokotos G, Verger R, Chiou A
    CHEM-EUR J 6 (22): 4211-4217 NOV 17 2000
44. Inhibition of lipoprotein lipase by alkanesulfonyl fluorides
    Kokotos G, Kotsovolou S, Constantinou-Kokotou V, Wu GS, Olivecrona G
    BIOORG MED CHEM LETT 10 (24): 2803-2806 DEC 18 2000
45. Synthesis and fluorescence properties of intramolecularly quenched fluorogenic p-nitroanilides containing coumarin or quinolinone derivatives as fluorophores
    Charitos C, Tzougraki C, Kokotos G
    J PEPT RES 56 (6): 373-381 DEC 2000
46. Bis-2-oxo amide triacylglycerol analogues: A novel class of potent human gastric lipase inhibitors
    Kotsovolou S, Chiou A, Verger R, Kokotos G
    J ORG CHEM 66 (3): 962-967 FEB 9 2001
47. A novel approach to the synthesis of chiral terminal 1,2-diamines
    Markidis T, Kokotos G
    J ORG CHEM 66 (5): 1919-1923 MAR 9 2001
48. Synthesis and in vitro cytotoxicity of novel long chain busulphan analogues
    Kokotos G, Constantinou-Kokotou V, Padron JM, Peters GJ
    BIOORG MED CHEM LETT 11 (6): 861-863 MAR 26 2001
49. Bifunctional coumarin derivatives in solution and solid phase synthesis of fluorogenic enzyme substrates
    Charitos C, Kokotos G, Tzougraki C
    J HETEROCYCLIC CHEM 38 (1): 153-158 JAN-FEB 2001
50. Study of aminoglycoside-nucleic acid interactions by an HPLC method
    Constantinou-Kokotou V, Karikas G, Kokotos G
    BIOORG MED CHEM LETT 11 (8): 1015-1018 APR 23 2001
51. Synthetic routes and lipase-inhibiting activity of long-chain alpha-keto amides
    Chiou A, Verger R, Kokotos G
    LIPIDS 36 (5): 535-542 MAY 2001
52. Synthesis of enantiopure non-natural alpha-amino acids using tert-butyl (2S)-2-[bis(tert-butoxycarbonyl)amino]-5-oxopentanoate as key-intermediate: the first synthesis of (S)-2-amino-oleic acid
    Constantinou-Kokotou V, Magrioti V, Markidis T, Kokotos G
    J PEPT RES 58 (4): 325-331 OCT 2001
53. Synthesis and in vitro cytotoxicity of long chain 2-amino alcohols and 1,2-diamines
    Markidis T, Padron JM, Martin VS, Peters GJ, Kokotos G
    ANTICANCER RES 21 (4A): 2835-2839 JUL-AUG 2001
54. Synthesis of enantiopure omega-functionalized C15 alpha-amino carboxylates
    Markidis T, Kokotos G
    J ORG CHEM 67 (5): 1685-1688 MAR 8 2002
55. Novel 2-oxoamide inhibitors of human group IVA phospholipase A(2)
    Kokotos G, Kotsovolou S, Six DA, Constantinou-Kokotou V, Beltzner CC, Dennis EA
    J MED CHEM 45 (14): 2891-2893 JUL 4 2002
56. Synthesis of lipophilic aldehydes and study of their inhibition effect on human digestive lipases
    Kotsovolou S, Verger R, Kokotos G
    ORG LETT 4 (16): 2625-2628 AUG 8 2002
57. Synthesis of chiral n,n+1-diamino acids and their application to the construction of dendrimers
    Bellis E, Markidis T, Kokotos G
    SYNTHESIS-STUTTGART (10): 1359-1364 AUG 2002
58. An efficient method for the synthesis of enantiopure omega-amino acids with proteinogenic side chains
    Noula C, Loukas V, Kokotos G
    SYNTHESIS-STUTTGART (12): 1735-1739 SEP 2002
59. Amino acid based synthesis of chiral long chain diamines and tetramines
    Loukas V, Markidis T, Kokotos G
    MOLECULES 7 (10): 767-776 OCT 2002
60. Synthesis of 2-amino alcohols and unnatural amino acids from serine
    Magrioti V, Antonopoulou G, Pantoleon E, Kokotos G
    ARKIVOC : 55-61 Part 13 2002
61. Novel trifluoromethyl ketones as potent gastric lipase inhibitors
    Kokotos G, Kotsovolou S, Verger R
    CHEMBIOCHEM 4 (1): 90-95 JAN 3 2003
62. Efficient protocols for the synthesis of enantiopure gamma-amino acids with proteinogenic side chains
    Loukas V, Noula C, Kokotos G
    J PEPT SCI 9 (5): 312-319 MAY 2003
63. Inhibition of digestive lipases by 2-oxo amide triacylglycerol analogues
    Kokotos G
    J MOL CATAL B-ENZYM 22 (5-6): 255-269 JUL 11 2003
64. Stereoselective intramolecular azide 1,3-dipolar cycloaddition
    Markidis T, Mikros E, Kokotos G
    HETEROCYCLES 60 (12): 2637-+ DEC 1 2003
65. Inhibition of group IVA cytosolic phospholipase A(2) by novel 2-oxoamides in vitro, in cells, and in vivo
    Kokotos G, Six DA, Loukas V, Smith T, Constantinou-Kokotou V, Hadjipavlou-Litina D, Kotsovolou S, Chiou A, Beltzner CC, Dennis EA
    J MED CHEM 47 (14): 3615-3628 JUL 1 2004
66. Homogeneous catalytic aminocarbonylation of iodoalkenes and iodobenzene with amino acid esters under conventional conditions and in ionic liquids
    Muller E, Peczely G, Skoda-Foldes R, Takacs E, Kokotos G, Bellis E, Kollar L
    TETRAHEDRON 61 (4): 797-802 JAN 24 2005
67. Enzymatic removal of carboxyl protecting groups. 1. Cleavage of the tert-butyl moiety
    Barbayianni E, Fotakopoulou I, Hohne M, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G
    J ORG CHEM 70 (9): 3737-3740 APR 29 2005
68. 4-Substituted prolines as organocatalysts for aldol reactions
    Bellis E, Kokotos G
    TETRAHEDRON 61 (36): 8669-8676 SEP 5 2005
69. Synthesis of non-natural amino acids based on the ruthenium-catalysed oxidation of a phenyl group to carboxylic acid
    Moutevelis-Minakakis P, Sinanoglou C, Loukas V, Kokotos G
    SYNTHESIS-STUTTGART (6): 933-938 APR 18 2005
70. 4-Substituted prolyl sulfonamides as enantioselective organocatalysts for aldol reactions
    Bellis E, Vasilatou K, Kokotos G
    SYNTHESIS-STUTTGART (14): 2407-2413 SEP 2 2005
71. Proline-modified poly (propyleneimine) dendrimers as catalysts for asymmetric aldol reactions
    Bellis E, Kokotos G
    J MOL CATAL A-CHEM 241 (1-2): 166-174 NOV 1 2005
72. Enzymatic removal of carboxyl protecting groups. 2. Cleavage of the benzyl and methyl moieties
    Barbayianni E, Fotakopoulou I, Schmidt M, Constantinou-Kokotou V, Bornscheuer UT, Kokotos G
    J ORG CHEM 70 (22): 8730-8733 OCT 28 2005
73. Systemic and intrathecal effects of a novel series of phospholipase A(2) inhibitors on hyperalgesia and spinal prostaglandin E-2 release
    Yaksh TL, Kokotos G, Svensson CI, et al.
    J PHARMACOL EXP THER 316 (1): 466-475 JAN 2006
74. Prolinates as secondary amines in aminocarbonylation: Synthesis of N-acylated prolinates
    Takacs E, Skoda-Foldes R, Acs P, et al.
    LETT ORG CHEM 3 (1): 62-67 JAN 2006
75. Differential inhibition of Group IVA and Group VIA phospholipases A(2) by 2-oxoamides
    Stephens D, Barbayianni E, Constantinou-Kokotou V, et al.
    J MED CHEM 49 (9): 2821-2828 MAY 4 2006
76. Synthesis of tetrazole analogs of gamma- and delta-amino acids
    Moutevelis-Minakakis P, Filippakou M, Sinanoglou C, et al.
    J PEPT SCI 12 (6): 377-382 JUN 2006
77. Three generations of alpha,gamma-diaminobutyric acid modified poly(propyleneimine) dendrimers and their cisplatin-type platinum complexes
    Bellis E, Hajba L, Kovacs B, et al.
    J BIOCHEM BIOPH METH 69 (1-2): 151-161 Sp. Iss. SI NOV 30 2006